diff --git a/django/db/models/indexes.py b/django/db/models/indexes.py
index 176f719fe5..a408506527 100644
--- a/django/db/models/indexes.py
+++ b/django/db/models/indexes.py
@@ -114,7 +114,12 @@ class Index:
                 )
         errors.extend(
             model._check_local_fields(
-                {*self.fields, *self.include, *references}, "indexes"
+                {
+                    *[field for field, _ in self.fields_orders],
+                    *self.include,
+                    *references,
+                },
+                "indexes",
             )
         )
         # Database-feature checks:
diff --git a/tests/invalid_models_tests/test_models.py b/tests/invalid_models_tests/test_models.py
index faa0db9da7..5780704eae 100644
--- a/tests/invalid_models_tests/test_models.py
+++ b/tests/invalid_models_tests/test_models.py
@@ -185,6 +185,15 @@ class IndexesTests(TestCase):
             ],
         )
 
+    def test_pointing_to_desc_field(self):
+        class Model(models.Model):
+            name = models.CharField(max_length=100)
+
+            class Meta:
+                indexes = [models.Index(fields=["-name"], name="index_name")]
+
+        self.assertEqual(Model.check(databases=self.databases), [])
+
     def test_pointing_to_m2m_field(self):
         class Model(models.Model):
             m2m = models.ManyToManyField("self")