diff --git a/django/contrib/admin/checks.py b/django/contrib/admin/checks.py
index 0fefe65e48..c395b0bde2 100644
--- a/django/contrib/admin/checks.py
+++ b/django/contrib/admin/checks.py
@@ -916,9 +916,10 @@ class ModelAdminChecks(BaseModelAdminChecks):
                         id="admin.E108",
                     )
                 ]
-        if isinstance(field, models.ManyToManyField) or (
-            getattr(field, "rel", None) and field.rel.field.many_to_one
-        ):
+        if (
+            getattr(field, "is_relation", False)
+            and (field.many_to_many or field.one_to_many)
+        ) or (getattr(field, "rel", None) and field.rel.field.many_to_one):
             return [
                 checks.Error(
                     f"The value of '{label}' must not be a many-to-many field or a "
diff --git a/tests/modeladmin/test_checks.py b/tests/modeladmin/test_checks.py
index 85f2eda69e..69aa242a64 100644
--- a/tests/modeladmin/test_checks.py
+++ b/tests/modeladmin/test_checks.py
@@ -554,6 +554,30 @@ class ListDisplayTests(CheckTestCase):
             "admin.E109",
         )
 
+    def test_invalid_related_field(self):
+        class TestModelAdmin(ModelAdmin):
+            list_display = ["song"]
+
+        self.assertIsInvalid(
+            TestModelAdmin,
+            Band,
+            "The value of 'list_display[0]' must not be a many-to-many field or a "
+            "reverse foreign key.",
+            "admin.E109",
+        )
+
+    def test_invalid_m2m_related_name(self):
+        class TestModelAdmin(ModelAdmin):
+            list_display = ["featured"]
+
+        self.assertIsInvalid(
+            TestModelAdmin,
+            Band,
+            "The value of 'list_display[0]' must not be a many-to-many field or a "
+            "reverse foreign key.",
+            "admin.E109",
+        )
+
     def test_valid_case(self):
         @admin.display
         def a_callable(obj):